Asthmagenicity of coal mine roof-bolting resins: an assessment using inhalation provocation tests.
R Convery, A Ward, R Ward, CL Bromly, JH Dennis, SC Stenton, SJ Bourke, DJ Hendrick
Occup Med (Lond) | Published : 2001
Inhalation provocation tests were used to assess whether the volatile products of an activated resin had caused occupational asthma in a non-random sample of six asthmatic coal miners. The resin system uses the polymerization of polyester and styrene under the influence of the cross-linking agent dibenzoyl peroxide to secure roof, wall and floor bolts in mine tunnels. The tests were conducted sequentially in a double-blind fashion over a 'dose' range which extended just beyond the maximum likely to have been experienced occupationally during a single day's work. The tests were monitored by symptoms, changes in the forced expiratory volume in 1 s (FEV1) and changes in airway responsiveness. A..View full abstract