Prevalence of Sarcopenia and Relationships Between Muscle and Bone in Indian Men and Women
Ayse Zengin, Bharati Kulkarni, Anuradha V Khadilkar, Neha Kajale, Veena Ekbote, Nikhil Tandon, Santosh K Bhargava, Harshpal Singh Sachdev, Shikha Sinha, David Scott, Sanjay Kinra, Caroline HD Fall, Peter R Ebeling
CALCIFIED TISSUE INTERNATIONAL | SPRINGER | Published : 2021
Both ethnicity and age are important determinants of musculoskeletal health. We aimed to determine the prevalence of sarcopenia, assess the suitability of current diagnostic guidelines, and explore muscle-bone relationships in adults from India. A total of 1009 young (20-35 years) and 1755 older (> 40 years) men and women from existing studies were collated and pooled for the analysis. Dual-energy x-ray absorptiometry measured areal bone mineral density (aBMD) at the hip and spine, and fat and lean mass; hand dynamometer measured hand grip strength (HGS). Indian-specific cut-points for appendicular lean mass (ALM), ALM index (ALMI) and HGS were calculated from young Indian (-2SD mean) popula..View full abstract
Awarded by Wellcome Trust Strategic Award
Awarded by Wellcome Trust project Grant
This work was supported by the Australian Academy of Sciences, Australia-India Early and Mid-Career Fellowships (AZ). The third survey wave of APCAPS was funded by Wellcome Trust Strategic Award (084774). IMS was funded by the Wellcome Trust project Grant (GR070797MF). NDBC was funded by the Indian Council of Medical Research, British Heart Foundation, the Wellcome Trust UK, the Medical Research Council UK, the National Institute for Health Research Nutrition and Metabolism Biomedical Research Unit, University of Southampton and the National Institute for Health Research Musculoskeletal Biomedical Research Unit, University of Oxford.