CoffeeProt: an online tool for correlation and functional enrichment of systems genetics data
Jeffrey Molendijk, Marcus M Seldin, Benjamin L Parker
NUCLEIC ACIDS RESEARCH | OXFORD UNIV PRESS | Published : 2021
The integration of genomics, transcriptomics, proteomics and phenotypic traits across genetically diverse populations is a powerful approach to discover novel biological regulators. The increasing volume of complex data require new and easy-to-use tools accessible to a variety of scientists for the discovery and visualization of functionally relevant associations. To meet this requirement, we developed CoffeeProt, an open-source tool that analyses genetic variants associated to protein networks, other omics datatypes and phenotypic traits. CoffeeProt uses transcriptomics or proteomics data to perform correlation network analyses and annotates results with protein-protein interactions, subcel..View full abstract
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Awarded by Australian National Health and Medical Research Council
Awarded by National Institute of Health
Australian National Health and Medical Research Council Ideas Grant [APP1184363]; B.L.P. is supported by the University of Melbourne Driving Research Momentum program; M.M.S. is supported by National Institute of Health [DK097771, HL138193]. Funding for open access charge: University of Melbourne.