Evidence for acquisition of virulence effectors in pathogenic chytrids
Guiling Sun, Zefeng Yang, Tiffany Kosch, Kyle Summers, Jinling Huang
BMC Evolutionary Biology | BIOMED CENTRAL LTD | Published : 2011
BACKGROUND: The decline in amphibian populations across the world is frequently linked to the infection of the chytrid fungus Batrachochytrium dendrobatidis (Bd). This is particularly perplexing because Bd was only recently discovered in 1999 and no chytrid fungus had previously been identified as a vertebrate pathogen. RESULTS: In this study, we show that two large families of known virulence effector genes, crinkler (CRN) proteins and serine peptidases, were acquired by Bd from oomycete pathogens and bacteria, respectively. These two families have been duplicated after their acquisition by Bd. Additional selection analyses indicate that both families evolved under strong positive selection..View full abstract
Awarded by NSF Assembling the Tree of Life (ATOL)
Awarded by Division Of Environmental Biology
This work is supported in part by a NSF Assembling the Tree of Life (ATOL) grant (DEB 0830024).