Discovery of novel representatives of bilaterian neuropeptide families and reconstruction of neuropeptide precursor evolution in ophiuroid echinoderms.
Meet Zandawala, Ismail Moghul, Luis Alfonso Yañez Guerra, Jérôme Delroisse, Nikara Abylkassimova, Andrew F Hugall, Timothy D O'Hara, Maurice R Elphick
Open Biology | Published : 2017
Neuropeptides are a diverse class of intercellular signalling molecules that mediate neuronal regulation of many physiological and behavioural processes. Recent advances in genome/transcriptome sequencing are enabling identification of neuropeptide precursor proteins in species from a growing variety of animal taxa, providing new insights into the evolution of neuropeptide signalling. Here, detailed analysis of transcriptome sequence data from three brittle star species, Ophionotus victoriae, Amphiura filiformis and Ophiopsila aranea, has enabled the first comprehensive identification of neuropeptide precursors in the class Ophiuroidea of the phylum Echinodermata. Representatives of over 30 ..View full abstract
Awarded by Biotechnology and Biological Sciences Research Council