Journal article

Efficacy and Safety of Traditional Chinese Herbal Medicine for Antipsychotic-Related Constipation: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Wen-Wang Rao, Juan-Juan Yang, Han Qi, Sha Sha, Wei Zheng, Ling Zhang, Gabor S Ungvari, Chee H Ng, Yu-Tao Xiang

FRONTIERS IN PSYCHIATRY | FRONTIERS MEDIA SA | Published : 2021

Abstract

Background: Constipation is a common but often ignored side effect of antipsychotic treatment, although it is associated with adverse outcomes. The results of the efficacy and safety of traditional Chinese herbal medicine (TCM) in treating constipation are mixed across studies. This is a systematic review and meta-analysis of randomized controlled trials (RCTs) of the efficacy and safety of TCM compared to Western medicine (WM) in treating antipsychotic-related constipation. Methods: Major international electronic (PubMed, EMBASE, Cochrane Library, and Web of Science) and Chinese (Wanfang, WeiPu VIP, SinoMed, and CNKI) databases were searched from their inception to November 29, 2020. Meta-a..

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University of Melbourne Researchers

Grants

Awarded by National Science and Technology Major Project for investigational new drug


Awarded by Beijing Municipal Science and Technology Commission


Awarded by University of Macau


Funding Acknowledgements

This study was supported by the National Science and Technology Major Project for investigational new drug (2018ZX09201-014), the Beijing Municipal Science and Technology Commission (No. Z181100001518005), and the University of Macau (MYRG2019-00066-FHS).