Journal article

Exercise attenuates bone mineral density loss during diet-induced weight loss in adults with overweight and obesity: A systematic review and meta-analysis

Jakub Mesinovic, Paul Jansons, Ayse Zengin, Barbora de Courten, Alexander J Rodriguez, Robin M Daly, Peter R Ebeling, David Scott

JOURNAL OF SPORT AND HEALTH SCIENCE | SHANGHAI UNIV SPORT | Published : 2021

Abstract

BACKGROUND: Weight-loss-induced fat loss improves cardiometabolic health in individuals with overweight and obesity; however, weight loss can also result in bone loss and increased fracture risk. Weight-loss-induced bone loss may be attenuated with exercise. Our aim was to compare changes in bone mineral density (BMD) in adults with overweight and obesity who undertook diet-induced weight loss alone or in combination with exercise. METHODS: We included randomized controlled trials (RCTs) in adults with overweight or obesity (aged ≥18 years; body mass index ≥25 kg/m2) that prescribed diet-induced weight loss alone or in combination with supervised exercise, and measured any bone structural pa..

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University of Melbourne Researchers

Grants

Awarded by Australian National Health and Medical Research Council (NHMRC) RD Wright Biomedical Career Development Fellowship


Awarded by NHMRC Investigator Grant


Funding Acknowledgements

JM is supported by a Research Training Program Scholarship; DS is supported by an Australian National Health and Medical Research Council (NHMRC) RD Wright Biomedical Career Development Fellowship (GNT1123014) and an NHMRC Investigator Grant (GNT1174886).