Journal article

Grand multiparity associations with low bone mineral density and degraded trabecular bone pattern

Nekoo Panahi, Afshin Ostovar, Noushin Fahimfar, Safoora Gharibzadeh, Gita Shafiee, Ramin Heshmat, Alireza Raeisi, Iraj Nabipour, Bagher Larijani, Ali Ghasem-Zadeh

BONE REPORTS | ELSEVIER | Published : 2021

Abstract

Introduction: Pregnancy is associated with changes in bone remodeling and calcium metabolism, which may increase the risk of fragility fracture after menopause. We hypothesized that in postmenopausal women, with history of grand multiparity, the magnitude of trabecular bone deterioration is associated with number of deliveries. Methods: 1217 women aged 69.2 ± 6.4 years, from the Bushehr Elderly Health (BEH) program were recruited. The areal bone mineral density (aBMD) of the lumbar spine and femoral neck and trabecular bone score (TBS) of 916 postmenopausal women, with grand multiparity defined as more than 4 deliveries, were compared with those of 301 postmenopausal women with 4 or fewer de..

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University of Melbourne Researchers