Journal article
Modeling the Cost-Effectiveness of Latent Tuberculosis Screening and Treatment Strategies in Recent Migrants to a Low-Incidence Setting
KD Dale, MJ Abayawardana, ES Mcbryde, JM Trauer, N Carvalho
American Journal of Epidemiology | OXFORD UNIV PRESS INC | Published : 2022
DOI: 10.1093/aje/kwab150
Abstract
Many tuberculosis (TB) cases in low-incidence settings are attributed to reactivation of latent TB infection (LTBI) acquired overseas. We assessed the cost-effectiveness of community-based LTBI screening and treatment strategies in recent migrants to a low-incidence setting (Australia). A decision-analytical Markov model was developed that cycled 1 migrant cohort (≥11-year-olds) annually over a lifetime from 2020. Postmigration/onshore and offshore (screening during visa application) strategies were compared with existing policy (chest X-ray during visa application). Outcomes included TB cases averted and discounted cost per quality-adjusted life-year (QALY) gained from a health-sector persp..
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Awarded by National Health and Medical Research Council
Funding Acknowledgements
This work was supported by The Miller Foundation, which funded the Miller Foundation Scholarship for Infection and Immunity, granted to K.D.D. toward her doctoral studies. This work was also supported by an Early Career Fellowship from the National Health and Medical Research Council (grant APP1142638) granted to J.M.T.