A phantom study to contrast and compare polymer and gold fiducial markers in radiotherapy simulation imaging.
Daryl Lim Joon, Drew Smith, Mark Tacey, Michal Schneider, Benjamin Harris, Wee Loon Ong, Farshad Foroudi, Trish Jenkins, Morikatsu Wada, Michael Chao, Kym Rykers, Vincent Khoo
Sci Rep | Published : 2021
To assess visibility and artifact characteristics of polymer fiducials compared to standard gold fiducials for radiotherapy CT and MRI simulation. Three gold and three polymer fiducials were inserted into a CT and MRI tissue-equivalent phantom that approximated the prostate cancer radiotherapy configuration. The phantom and fiducials were imaged on CT and MRI. Images were assessed in terms of fiducial visibility and artifact. ImageJ was employed to quantify the pixel gray-scale of each fiducial and artifact. Fiducial gray-scale histograms and profiles were generated for analysis. Objective measurements of the contrast-to-noise ratio (CNR), signal-to-noise ratio (SNR), and artifact index (AI)..View full abstract