Journal article

047 Fear-Potentiated Startle and Sleep in Trauma-Exposed Men and Women with and without PTSD

Anne Richards, Sabra Inslicht, J Russell Huie, Leslie Yack, Laura Straus, Kim Felmingham, Steve Woodward, Thomas Neylan

Sleep | Oxford University Press (OUP) | Published : 2021

Abstract

Abstract Introduction Animal and human studies indicate that fear conditioning disrupts subsequent sleep, including REM sleep (REMS). REMS is thought to be central to fear information processing. We utilized an afternoon nap protocol to examine the effects of fear-potentiated startle (FPS), a variant of fear conditioning, on subsequent sleep integrity and REMS in trauma-exposed participants with varying levels of PTSD. We also examined the effects of changes in sleep integrity and REMS on subsequent retention and extinction of pre-sleep learning. Methods Participants (N=47)..

View full abstract