The Impact on 30-Day Mortality From a Brief Focused Ultrasound-Guided Management Protocol Immediately Before Emergency Noncardiac Surgery in Critically Ill Patients: A Multicenter Randomized Controlled Trial

Abstract

Objective: To determine whether brief ultrasound-guided treatment of hemodynamic shock and respiratory failure immediately before emergency noncardiac surgery reduced 30-day mortality. Design: Parallel, nonblinded, randomized trial with 1:1 allocation to control and intervention groups. Setting: Twenty-eight major hospitals within China. Participants: Six-hundred sixty patients ≥14 years of age, scheduled for emergency noncardiac surgery with evidence of shock (heart rate >120 beat/min, systolic blood pressure< 90 mmHg or requiring inotrope infusion), or respiratory failure (Pulse Oxygen Saturation 20 beat/min, or requiring mechanical ventilation). Interventions: A brief (<15 minutes) focuse..