Journal article

Pregnancy Outcomes in COVID-19: A Prospective Cohort Study in Singapore

Citra NZ Mattar, Shirin Kalimuddin, Sapna P Sadarangani, Shephali Tagore, Serene Thain, Koh Cheng Thoon, Eliane Y Hong, Abhiram Kanneganti, Chee Wai Ku, Grace MF Chan, Kelvin ZX Lee, Jeannie JY Yap, Shaun S Tan, Benedict Yan, Barnaby E Young, David C Lye, Danielle E Anderson, Liying Yang, Lin Lin Su, Jyoti Somani Show all

Annals, Academy of Medicine, Singapore | ACAD MEDICINE SINGAPORE | Published : 2020

Abstract

INTRODUCTION: Pregnant women are reported to be at increased risk of severe coronavirus disease 2019 (COVID-19) due to underlying immunosuppression during pregnancy. However, the clinical course of COVID-19 in pregnancy and risk of vertical and horizontal transmission remain relatively unknown. We aim to describe and evaluate outcomes in pregnant women with COVID-19 in Singapore. METHODS: Prospective observational study of 16 pregnant patients admitted for COVID-19 to 4 tertiary hospitals in Singapore. Outcomes included severe disease, pregnancy loss, and vertical and horizontal transmission. RESULTS: Of the 16 patients, 37.5%, 43.8% and 18.7% were infected in the first, second and third tri..

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