Journal article

Viruses in bats and potential spillover to animals and humans

Lin-Fa Wang, Danielle E Anderson

Current Opinion in Virology | ELSEVIER SCI LTD | Published : 2019

Abstract

In the last two decades, several high impact zoonotic disease outbreaks have been linked to bat-borne viruses. These include SARS coronavirus, Hendra virus and Nipah virus. In addition, it has been suspected that ebolaviruses and MERS coronavirus are also linked to bats. It is being increasingly accepted that bats are potential reservoirs of a large number of known and unknown viruses, many of which could spillover into animal and human populations. However, our knowledge into basic bat biology and immunology is very limited and we have little understanding of major factors contributing to the risk of bat virus spillover events. Here we provide a brief review of the latest findings in bat vi..

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Grants

Awarded by National Research Foundation


Awarded by Ministry of Health


Awarded by Ministry of Defence in Singapore


Awarded by Estate of Tan Sri Khoo Teck Puat


Funding Acknowledgements

We thank Xiao Fang Lim, Xinglou Yang and Anna Uehara for help with Figure 1, Figure 3 and Table 1, respectively. We are grateful to Andrew Hickey for critical review of the manuscript. The research in L-FW's group is funded by the National Research Foundation [NRF2012NRF-CRP001-056 and NRF2016NRF-NSFC002-013], Ministry of Health [CDPHRG/0006/2014] and Ministry of Defence [DIRP2015-9016102060] in Singapore. Research in DEA's group is funded by Duke-NUS Medical School and the Estate of Tan Sri Khoo Teck Puat [NUS-KBrFA/2018/0016].