Outbreak of Zika virus infection in Singapore: an epidemiological, entomological, virological, and clinical analysis
Zheng Jie Marc Ho, Hapuarachchige Chanditha Hapuarachchi, Timothy Barkham, Li Ping Angela Chow, Lee Ching Ng, Jian Ming Vernon Lee, Yee Sin Leo, Kiesha Prem, Yue Hui Georgina Lim, Paola F de Sessions, Maia A Rabaa, Chee Seng Chong, Cheong Huat Tan, Jayanthi Rajarethinam, Junhao Tan, Danielle E Anderson, Xinmei Ong, Alex R Cook, Chia Yin Chong, Li Yang Hsu Show all
The Lancet Infectious Diseases | ELSEVIER SCI LTD | Published : 2017
BACKGROUND: An outbreak of Zika virus infection was detected in Singapore in August, 2016. We report the first comprehensive analysis of a national response to an outbreak of Zika virus infection in Asia. METHODS: In the first phase of the outbreak, patients with suspected Zika virus infection were isolated in two national referral hospitals until their serum tested negative for the virus. Enhanced vector control and community engagement measures were deployed in disease clusters, including stepped-up mosquito larvicide and adulticide use, community participation in source reduction (destruction of mosquito breeding sites), and work with the local media to promote awareness of the outbreak. ..View full abstract
National Medical Research Council Singapore, Centre for Infectious Disease Epidemiology and Research, and A<SUP>star</SUP>STAR Biomedical Research Council.