Journal article

Cognitive Recovery After Stroke: A Meta-analysis and Metaregression of Intervention and Cohort Studies

Juan Pablo Saa, Tamara Tse, Carolyn M Baum, Toby Cumming, Naomi Josman, Miranda Rose, Sophie O'Keefe, Katherine Sewell, Vinh Nguyen, Leeanne M Carey

NEUROREHABILITATION AND NEURAL REPAIR | SAGE PUBLICATIONS INC | Published : 2021

Abstract

BACKGROUND: Cognition affects poststroke recovery, but meta-analyses of cognition have not yet provided a comparison of observational and intervention evidence. OBJECTIVE: To describe the trajectory of poststroke cognition and the factors that moderate it across intervention and observational cohorts. METHODS: Six databases were searched up to January 2020. Studies describing quantitative changes in cognition in adults poststroke were included. Interventions were classified into pharmacological, therapist-led, nonroutine/alternative, and usual care. Summary estimates were compared via hierarchical mixed-effects models. Age, recovery stage, stroke etiology, cognitive domain targeted in studie..

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Grants

Awarded by James S. McDonnell Foundation


Awarded by National Health and Medical Research Council of Australia (NHMRC)


Funding Acknowledgements

The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: James S. McDonnell Foundation (Cognitive Rehabilitation Collaborative Award 220020413), Commonwealth Science and Industrial Research Organisation (CSIRO) flagship collaborative fund, National Health and Medical Research Council of Australia (NHMRC, Awards 1077898, 1153236, 1113352 and 2004443), and a La Trobe University Postgraduate Research Grant (LTUPRS).