Cognitive Recovery After Stroke: A Meta-analysis and Metaregression of Intervention and Cohort Studies
Juan Pablo Saa, Tamara Tse, Carolyn M Baum, Toby Cumming, Naomi Josman, Miranda Rose, Sophie O'Keefe, Katherine Sewell, Vinh Nguyen, Leeanne M Carey
NEUROREHABILITATION AND NEURAL REPAIR | SAGE PUBLICATIONS INC | Published : 2021
BACKGROUND: Cognition affects poststroke recovery, but meta-analyses of cognition have not yet provided a comparison of observational and intervention evidence. OBJECTIVE: To describe the trajectory of poststroke cognition and the factors that moderate it across intervention and observational cohorts. METHODS: Six databases were searched up to January 2020. Studies describing quantitative changes in cognition in adults poststroke were included. Interventions were classified into pharmacological, therapist-led, nonroutine/alternative, and usual care. Summary estimates were compared via hierarchical mixed-effects models. Age, recovery stage, stroke etiology, cognitive domain targeted in studie..View full abstract
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Awarded by James S. McDonnell Foundation
Awarded by National Health and Medical Research Council of Australia (NHMRC)
The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: James S. McDonnell Foundation (Cognitive Rehabilitation Collaborative Award 220020413), Commonwealth Science and Industrial Research Organisation (CSIRO) flagship collaborative fund, National Health and Medical Research Council of Australia (NHMRC, Awards 1077898, 1153236, 1113352 and 2004443), and a La Trobe University Postgraduate Research Grant (LTUPRS).