Journal article

Community-based molecular and serological surveillance of subclinical malaria in Myanmar

Katherine O'Flaherty, Win Han Oo, Sophie G Zaloumis, Julia C Cutts, Kyaw Zayar Aung, Myat Mon Thein, Damien R Drew, Zahra Razook, Alyssa E Barry, Naanki Parischa, Nyi Nyi Zaw, Htin Kyaw Thu, Aung Thi, Wai Yan Min Htay, Aung Paing Soe, Julie A Simpson, James G Beeson, Paul A Agius, Freya JI Fowkes

BMC MEDICINE | BMC | Published : 2021

Abstract

BACKGROUND: In the Greater Mekong Subregion (GMS), current malaria surveillance strategies rely on a network of village health volunteers (VHVs) reporting the results of rapid diagnostic tests (RDTs), known to miss many asymptomatic infections. Integration of more sensitive diagnostic molecular and serological measures into the VHV network may improve surveillance of residual malaria transmission in hard-to-reach areas in the region and inform targeted interventions and elimination responses. However, data on residual malaria transmission that would be captured by these measures in the VHV-led testing and treatment surveillance network in the GMS is unknown. METHODS: A total of 114 VHVs were..

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Grants

Awarded by Three Millennium Development Goal (3MDG) fund


Awarded by Australian Research Council


Awarded by National Health and Medical Research Council (Australian Centre for Research Excellence in Malaria Elimination (ACREME))


Awarded by Career Development Fellowship


Awarded by Senior Research Fellowship



Funding Acknowledgements

The implementation of malaria services in Myanmar was supported by the Three Millennium Development Goal (3MDG) fund (BI-MARC-3MDG-C2-1400089847). Further funding was received from the Australian Research Council (Future Fellowship to FJIF, FT130101122) and the National Health and Medical Research Council (Australian Centre for Research Excellence in Malaria Elimination (ACREME) to FJIF, JAS, JGB (1134989); Career Development Fellowship to FJIF (1166753); Senior Research Fellowship to JAS (1104975); Investigator Grant (1173046) and Programme Grant (1092789) to JGB; and its Independent Research Institute Infrastructure Support Scheme). The authors gratefully acknowledge the contribution to this work of the Victorian Operational Infrastructure Support Program received by the Burnet Institute. The funders had no role in the study design, data collection and analysis, decision to publish or preparation of the manuscript.