Predictors of death and new disability after critical illness: a multicentre prospective cohort study
AM Higgins, A Serpa Neto, M Bailey, J Barrett, R Bellomo, DJ Cooper, BJ Gabbe, N Linke, PS Myles, M Paton, S Philpot, M Shulman, M Young, CL Hodgson
INTENSIVE CARE MEDICINE | SPRINGER | Published : 2021
PURPOSE: This study aimed to determine the prevalence and predictors of death or new disability following critical illness. METHODS: Prospective, multicentre cohort study conducted in six metropolitan intensive care units (ICU). Participants were adults admitted to the ICU who received more than 24 h of mechanical ventilation. The primary outcome was death or new disability at 6 months, with new disability defined by a 10% increase in the WHODAS 2.0. RESULTS: Of 628 patients with the primary outcome available (median age of 62 [49-71] years, 379 [61.0%] had a medical admission and 370 (58.9%) died or developed new disability by 6 months. Independent predictors of death or new disability incl..View full abstract
Awarded by National Health and Medical Research Council of Australia
Awarded by National Health and Medical Research Council Investigator Grant
Awarded by Australian Research Council Future Fellowship
The PREDICT Study was funded by the National Health and Medical Research Council of Australia (GNT1132976). Professor Hodgson is supported by a Heart Foundation Fellowship and a National Health and Medical Research Council Investigator Grant (GNT1173271). Professor Gabbe is supported by an Australian Research Council Future Fellowship (FT170100048). The funding agencies had no role in the design and conduct of the study; collection, management, analysis and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.