Journal article

Predictors of death and new disability after critical illness: a multicentre prospective cohort study

AM Higgins, A Serpa Neto, M Bailey, J Barrett, R Bellomo, DJ Cooper, BJ Gabbe, N Linke, PS Myles, M Paton, S Philpot, M Shulman, M Young, CL Hodgson

INTENSIVE CARE MEDICINE | SPRINGER | Published : 2021

Abstract

PURPOSE: This study aimed to determine the prevalence and predictors of death or new disability following critical illness. METHODS: Prospective, multicentre cohort study conducted in six metropolitan intensive care units (ICU). Participants were adults admitted to the ICU who received more than 24 h of mechanical ventilation. The primary outcome was death or new disability at 6 months, with new disability defined by a 10% increase in the WHODAS 2.0. RESULTS: Of 628 patients with the primary outcome available (median age of 62 [49-71] years, 379 [61.0%] had a medical admission and 370 (58.9%) died or developed new disability by 6 months. Independent predictors of death or new disability incl..

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University of Melbourne Researchers

Grants

Awarded by National Health and Medical Research Council of Australia


Awarded by National Health and Medical Research Council Investigator Grant


Awarded by Australian Research Council Future Fellowship


Funding Acknowledgements

The PREDICT Study was funded by the National Health and Medical Research Council of Australia (GNT1132976). Professor Hodgson is supported by a Heart Foundation Fellowship and a National Health and Medical Research Council Investigator Grant (GNT1173271). Professor Gabbe is supported by an Australian Research Council Future Fellowship (FT170100048). The funding agencies had no role in the design and conduct of the study; collection, management, analysis and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.