Journal article

Tracking the international spread of SARS-CoV-2 lineages B.1.1.7 and B.1.351/501Y-V2 with grinch.

Áine O'Toole, Verity Hill, Oliver G Pybus, Alexander Watts, Issac I Bogoch, Kamran Khan, Jane P Messina, undefined COVID-19 Genomics UK (COG-UK) consortium, undefined Network for Genomic Surveillance in South Africa (NGS-SA), undefined Brazil-UK CADDE Genomic Network, Houriiyah Tegally, Richard R Lessells, Jennifer Giandhari, Sureshnee Pillay, Kefentse Arnold Tumedi, Gape Nyepetsi, Malebogo Kebabonye, Maitshwarelo Matsheka, Madisa Mine, Sima Tokajian Show all

Wellcome Open Res | Published : 2021


Late in 2020, two genetically-distinct clusters of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with mutations of biological concern were reported, one in the United Kingdom and one in South Africa. Using a combination of data from routine surveillance, genomic sequencing and international travel we track the international dispersal of lineages B.1.1.7 and B.1.351 (variant 501Y-V2). We account for potential biases in genomic surveillance efforts by including passenger volumes from location of where the lineage was first reported, London and South Africa respectively. Using the software tool grinch (global report investigating novel coronavirus haplotypes), we track the intern..

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University of Melbourne Researchers


Awarded by Wellcome Trust

Awarded by Wellcome Trust and Royal Society Sir Henry Dale Fellowship

Awarded by Fast Grants

Awarded by Medical Research Council-São Paulo Research Foundation CADDE partnership award

Awarded by Instituto de Salud Carlos III

Awarded by Deutsche Forschungsgemeinschaft

Awarded by Canadian Institutes of Health Research, COVID-19 Rapid Research Funding Opportunity

Awarded by Biotechnology and Biological Sciences Research Council

Awarded by EU grant

Awarded by European Research Council