Journal article

The impacts of long-term exposure to PM2.(5) on cancer hospitalizations in Brazil

Pei Yu, Rongbin Xu, Micheline SZS Coelho, Paulo HN Saldiva, Shanshan Li, Qi Zhao, Ajay Mahal, Malcolm Sim, Michael J Abramson, Yuming Guo

ENVIRONMENT INTERNATIONAL | PERGAMON-ELSEVIER SCIENCE LTD | Published : 2021

Abstract

BACKGROUND: Long-term exposure to PM2.5 has been linked to cancer incidence and mortality. However, it was unknown whether there was an association with cancer hospitalizations. METHODS: Data on cancer hospitalizations and annual PM2.5 concentrations were collected from 1,814 Brazilian cities during 2002-2015. A difference-in-difference approach with quasi-Poisson regression was applied to examine State-specific associations. The State-specific associations were pooled at a national level using random-effect meta-analyses. PM2.5 attributable burden were estimated for cancer hospitalization admissions, inpatient days and costs. RESULTS: We included 5,102,358 cancer hospitalizations (53.8% fem..

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Grants

Awarded by China Scholarship Council funds


Awarded by Early Career Fellowship of the Australian National Health and Medical Research Council


Awarded by Australian National Health and Medical Research Council


Funding Acknowledgements

The authors thank the Brazilian Ministry of Health and Brazilian National Institute of Meteorology for providing hospitalization and meteorological data. PY, RX were supported by China Scholarship Council funds (number 201906210065 for PY, 201806010405 for RX); SL by an Early Career Fellowship of the Australian National Health and Medical Research Council (number APP1109193); and YG by Career Development Fellowships of the Australian National Health and Medical Research Council (numbers APP1107107 and APP1163693).