Journal article

Infection-Related Mortality in Adults and Children Undergoing Allogeneic Hematopoietic Cell Transplantation: An Australian Registry Report

Julian Lindsay, Ian Kerridge, Leonie Wilcox, Steven Tran, Tracey A O'Brien, Matthew Greenwood, Sharon C-A Chen, David CM Kong, Steven A Pergam, Catherine Liu, Monica A Slavin

TRANSPLANTATION AND CELLULAR THERAPY | ELSEVIER SCIENCE INC | Published : 2021

Abstract

Infection-related mortality (IRM) is the most common non-relapse-related cause of death reported after allogeneic hematopoietic cell transplantation (HCT). Information on the incidence and timing of specific infective organisms and the risk factors for IRM is essential to developing prevention strategies. This report provides the first account of IRM in adults and children undergoing HCT in Australia. Between 2013 and 2018, 2705 adult and 689 pediatric first HCTs were identified from the Australasian Bone Marrow Transplant Recipient Registry database, associated with 1075 (39.7%) total overall deaths in adults and 134 (19.4%) in children. Demographics and causes of death, including infectiou..

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