Journal article

The interaction with fungal cell wall polysaccharides determines the salt tolerance of antifungal plant defensins.

Mark R Bleackley, Charlotte S Dawson, Jennifer AE Payne, Peta J Harvey, K Johan Rosengren, Pedro Quimbar, Donovan Garcia-Ceron, Rohan Lowe, Vincent Bulone, Nicole L van der Weerden, David J Craik, Marilyn A Anderson

Cell Surf | Published : 2019


The fungal cell wall is the first point of contact between fungal pathogens and host organisms. It serves as a protective barrier against biotic and abiotic stresses and as a signal to the host that a fungal pathogen is present. The fungal cell wall is made predominantly of carbohydrates and glycoproteins, many of which serve as binding receptors for host defence molecules or activate host immune responses through interactions with membrane-bound receptors. Plant defensins are a large family of cationic antifungal peptides that protect plants against fungal disease. Binding of the plant defensin NaD1 to the fungal cell wall has been described but the specific component of the cell wall with ..

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University of Melbourne Researchers