Journal article
Sex-dependent associations between maternal prenatal stressful life events, BMI trajectories and obesity risk in offspring: The Raine Study
EV Bräuner, YH Lim, T Koch, TA Mori, L Beilin, DA Doherty, A Juul, R Hart, M Hickey
Comprehensive Psychoneuroendocrinology | ELSEVIER | Published : 2021
Abstract
Background: There is a high and growing prevalence of childhood obesity which increases the risk of adult obesity and adverse physical and mental health outcomes in adulthood. Experimental and clinical data suggest that the early life environment, particularly prenatal stress, may program development of obesity in the offspring. But few studies have assessed the associations between prenatal maternal stress and rapid (ascending) weight gain, which is the strongest predictor of adult obesity and metabolic disease. Experimental data indicate that the associations may be sex dependent, but the sex-dependent association between prenatal stress and growth in the human offspring during childhood a..
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Funding Acknowledgements
The core management of the Raine Study is funded by University of Western Australia, Curtin University, Telethon Kids Institute, Women and Infants Research Foundation, Edith Cowan University, Murdoch University, The University of Notre Dame Australia and Raine Medical Research foundation for providing funding to core management of the Raine Study. The Raine Study Gen2-14 year follow-up: NHMRC (Sly et al., ID 211912) ; NHMRC Program Grant (Stanley et al., ID 003209) . The Raine Medical Research Foundation. The research being reported in this publication was funded by The Health Foundation of Denmark (Helsefonden, Grant no. 18-B-0016) , The Danish Cancer Society (Kraeftens Bekaempelse, R204-A12636, Denmark) and Doctor Sofus Carl Emil Friis and spouse Olga Doris Friis foundation. The funding covered salary for Trine Koch and Elvira Brauner. Martha Hickey and Trevor Mori are funded by NHMRC Practitioner (ID number 1193838) and Senior Research Fellowships, respectively. The funding bodies played no role in the design, collection, analysis, or interpretation of data; in the writing of the manuscript; or in the decision to submit the manuscript for publication.