Journal article

Effect of a multicomponent nutritional supplement on functional outcomes for Duchenne muscular dystrophy: A randomized controlled trial

Zoe E Davidson, Ian Hughes, Monique M Ryan, Andrew J Kornberg, Anita G Cairns, Kristi Jones, Meghan Hutchence, Hugo Sampaio, Margot Morrison, Helen Truby

CLINICAL NUTRITION | CHURCHILL LIVINGSTONE | Published : 2021

Abstract

BACKGROUND & AIMS: Duchenne muscular dystrophy (DMD) is an X-linked neuromuscular condition causing progressive muscle weakness and premature death. Whilst effective treatments such as gene therapy are developed, families often seek complementary therapies such as nutrition supplements to help their son maintain function; however, there is limited evidence supporting the use of nutritional supplements in DMD. This study aimed to compare the effect of a Standard nutritional supplement with an Enhanced nutritional supplement combining three nutriceuticals on functional outcomes in ambulatory boys with Duchenne muscular dystrophy (DMD). DESIGN: A 50-week double blinded, randomized, controlled c..

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Grants

Awarded by National Health and Medical Research Council


Funding Acknowledgements

Funding statement This work was supported by Save our Sons Duchenne Foundation, John T Reid Charitable Trusts, Muscular Dystrophy Australia, Murdoch Children's Research Institute, and National Health and Medical Research Council (grant #1031893 for MMR and ZED) . Product was supplied by Blackmores (Blackmores Kids Multi, Blackmores Vitamin D3, Blackmores Kids Fruity FishiesTM) .