Conference Proceedings
437 Construct validity assessment of the lupus low disease activity state (lldas) – a case based validity study
V Golder, M Huq, K Franklyn, A Calderone, A Lateef, CS Lau, A Lee, S Navarra, T Godfrey, S Oon, A Hoi, E Morand, M Nikpour
Poster Session | Lupus Foundation of America | Published : 2017
Open access
Abstract
To evaluate the construct validity of the Lupus Low Disease Activity State (LLDAS), a treatment target in systemic lupus erythematosus (SLE). Fifty SLE case summaries based on real patients were prepared and assessed independently for meeting the operational definition of LLDAS. Fifty international rheumatologists with expertise in SLE, but with no prior involvement in the LLDAS project, responded to a survey in which they were asked to categorise the disease activity state of each case as remission, low, moderate or high. Agreement between expert opinion and LLDAS was assessed using Cohen’s Kappa. Overall agreement between expert opinion and the operational definition of LLDAS was 77.96% (9..
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