Journal article

Appendiceal pseudomyxoma peritonei: predictors of recurrence and iterative surgery

Joseph C Kong, Michael P Flood, Glen R Guerra, Amanda Liesegang, Wen J Wong, Catherine Mitchell, Satish K Warrier, Sanjeev Naidu, Brian Meade, Nicholas Lutton, Alexander G Heriot



AIM: Appendiceal pseudomyxoma peritonei (PMP) is a rare entity, with recurrence rates up to 26% despite optimal cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC). Evidence specific to PMP originating from non-infiltrative appendiceal mucinous neoplasms (low grade - LAMN and high grade - HAMN) is lacking. The aim of this study was to identify patterns of recurrence and predictive factors for patients appropriate for iterative surgery. METHOD: A bi-institutional retrospective analysis was performed on patients undergoing complete cytoreduction and HIPEC for PMP derived from perforated LAMN or HAMN. Multivariate logistic regression was performed to identify indep..

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