Journal article

A Focus on "Bio" in Bio-Nanoscience: The Impact of Biological Factors on Nanomaterial Interactions

Christina Cortez-Jugo, Ewa Czuba-Wojnilowicz, Abigail Tan, Frank Caruso

ADVANCED HEALTHCARE MATERIALS | WILEY | Published : 2021

Abstract

Bio-nanoscience research encompasses studies on the interactions of nanomaterials with biological structures or what is commonly referred to as the biointerface. Fundamental studies on the influence of nanomaterial properties, including size, shape, composition, and charge, on the interaction with the biointerface have been central in bio-nanoscience to assess nanomaterial efficacy and safety for a range of biomedical applications. However, the state of the cells, tissues, or biological models can also influence the behavior of nanomaterials at the biointerface and their intracellular processing. Focusing on the "bio" in bio-nano, this review discusses the impact of biological properties at ..

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Grants

Awarded by Australian Research Council Centre of Excellence in Convergent Bio-Nano Science and Technology


Awarded by Australian National Health and Medical Research Council (NHMRC)


Awarded by NHMRC Senior Principal Research Fellowship


Funding Acknowledgements

This research was supported by the Australian Research Council Centre of Excellence in Convergent Bio-Nano Science and Technology (project number CE140100036), the Australian National Health and Medical Research Council (NHMRC; Program Grant GNT1149990), the Australian Centre for HIV and Hepatitis Virology Research (ACH<SUP>2</SUP>), and the Friedreich's Ataxia Research Alliance. F.C. acknowledges the award of an NHMRC Senior Principal Research Fellowship (GNT1135806). The authors thank Dr. Matthew Faria and Dr. Robert De Rose for helpful discussions and critical review of the manuscript. The authors thank Ms. Yingjie Hu and Mr. Zhixing Lin for helpful discussions on the preparation of some of the figures.