Journal article

Extubation generates lung volume inhomogeneity in preterm infants

Risha Bhatia, Hazel R Carlisle, Ruth K Armstrong, C Omar Farouk Kamlin, Peter G Davis, David G Tingay

ARCHIVES OF DISEASE IN CHILDHOOD-FETAL AND NEONATAL EDITION | BMJ PUBLISHING GROUP | Published : 2021

Abstract

OBJECTIVE: To evaluate the feasibility of electrical impedance tomography (EIT) to describe the regional tidal ventilation (VT) and change in end-expiratory lung volume (EELV) patterns in preterm infants during the process of extubation from invasive to non-invasive respiratory support. DESIGN: Prospective observational study. SETTING: Single-centre tertiary neonatal intensive care unit. PATIENTS: Preterm infants born <32 weeks' gestation who were being extubated to nasal continuous positive airway pressure as per clinician discretion. INTERVENTIONS: EIT measurements were taken in supine infants during elective extubation from synchronised positive pressure ventilation (SIPPV) before extubat..

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Grants

Awarded by National Health and Medical Research Council Clinical Career Development Fellowship


Awarded by NHMRC


Funding Acknowledgements

This study was supported by a National Health and Medical Research Council Clinical Career Development Fellowship Grant ID 1053889 and Grant ID 1009287 (DGT), NHMRC Practitioner Fellowship Grant ID 556600 (DGT) NHMRC Program Grant ID 384100 and the Victorian Government Operational Infrastructure Support Program (Melbourne, Australia).