Journal article

Diffusion MRI tractography for neurosurgery: the basics, current state, technical reliability and challenges

Joseph Yuan-Mou Yang, Chun-Hung Yeh, Cyril Poupon, Fernando Calamante

PHYSICS IN MEDICINE AND BIOLOGY | IOP PUBLISHING LTD | Published : 2021

Abstract

Diffusion magnetic resonance imaging (dMRI) tractography is currently the only imaging technique that allows for non-invasive delineation and visualisation of white matter (WM) tractsin vivo,prompting rapid advances in related fields of brain MRI research in recent years. One of its major clinical applications is for pre-surgical planning and intraoperative image guidance in neurosurgery, where knowledge about the location of WM tracts nearby the surgical target can be helpful to guide surgical resection and optimise post-surgical outcomes. Surgical injuries to these WM tracts can lead to permanent neurological and functional deficits, making the accuracy of tractography reconstructions para..

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Grants

Awarded by Royal Children's Hospital Foundation


Awarded by Ministry of Science and Technology of Taiwan


Awarded by National Health and Medical Research Council of Australia


Awarded by Australian Research Council


Funding Acknowledgements

JYMY receives position funding from the Royal Children's Hospital Foundation (RCH1000), and acknowledges the support from the Murdoch Children's Research Institute, Royal Children's Hospital, The University of Melbourne Department of Paediatrics and the Victorian Government's Operational Infrastructure Support Program. CHY is grateful to the Ministry of Science and Technology of Taiwan (MOST 109-2222-E-182-001-MY3) for the support. FC acknowledges the support of the National Health and Medical Research Council of Australia (APP1091593 and APP1117724) and the Australian Research Council (DP170101815).