Can you reduce your AGE?. Strategies to prevent AGE accumulation in diabetes
MT Coughlan, ME Cooper, MC Thomas
Drug Discovery Today: Therapeutic Strategies | Published : 2007
Advanced glycation end-products (AGEs) contribute to the development and progression of diabetic kidney disease. Several different strategies have been developed to prevent the accumulation of AGEs in experimental diabetes, many of which have proved highly effective in attenuating renal damage in experimental models, even the absence of blood glucose control. These data suggests that if AGEs can be directly treated, some of the complications of diabetes may also be prevented. © 2007.