Journal article

Varying contributions of three ryanodine receptor point mutations to diamide insecticide resistance in Plutella xylostella

Dong Jiang, Cheng Qian, Danhui Wang, Falong Wang, Shan Zhao, Yihua Yang, Simon W Baxter, Xingliang Wang, Yidong Wu

PEST MANAGEMENT SCIENCE | JOHN WILEY & SONS LTD | Published : 2021

Abstract

BACKGROUND: Although decoding the molecular mechanisms underlying insecticide resistance has often proven difficult, recent progress has revealed that specific mutations in the ryanodine receptor (RyR) of the diamondback moth, Plutella xylostella, can confer resistance to diamide insecticides. The extent to which specific RyR mutations contribute to the diamide resistance phenotype, the associated genetic traits and fitness costs remain limited. RESULTS: Three field-evolved PxRyR mutations (G4946E, I4790 M, and I4790 K) were respectively introgressed into a common susceptible background strain (IPP-S) of P. xylostella with marker-assisted backcrossing. The mutations alone can result in moder..

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University of Melbourne Researchers