Journal article

Valuation system connectivity is correlated with poly-drug use in young adults.

Kavinash Loganathan, Jinglei Lv, Vanessa Cropley, Andrew Zalesky, Eric Tatt Wei Ho

Neurosci Res | Published : 2021

Abstract

Poly-drug consumption contributes to fatal overdose in more than half of all poly-drug users. Analyzing decision-making networks may give insight into the motivations behind poly-drug use. We correlated average functional connectivity of the valuation system (VS), executive control system (ECS) and valuation-control complex (VCC) in a large population sample (n = 992) with drug use behaviour. VS connectivity is correlated with sedative use, ECS connectivity is separately correlated with hallucinogens and opiates. Network connectivity is also correlated with drug use via two-way interactions with other substances including alcohol and tobacco. These preliminary findings can contribute to our ..

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