Journal article

Gender-based clinical differences in evidence-based treatment for adolescent anorexia nervosa: analysis of aggregated randomized controlled trials

Sasha Gorrell, Elizabeth K Hughes, Susan M Sawyer, Savannah R Roberts, Jason M Nagata, Michele Yeo, James Lock, Daniel Le Grange

EATING AND WEIGHT DISORDERS-STUDIES ON ANOREXIA BULIMIA AND OBESITY | SPRINGER | Published : 2021

Abstract

PURPOSE: Boys represent a small proportion of samples in randomized clinical trials (RCT) investigating evidence-based treatment for adolescents with anorexia nervosa (AN). Consequently, knowledge of potential gender differences in clinical characteristics and treatment response in adolescents is considerably limited. METHODS: Secondary analyses of aggregated data from two RCTs were used to characterize baseline and end-of-treatment clinical features in male and female adolescents with AN (n = 228, 10.53% male). Mixed analyses of variance were used to investigate potential gender differences in treatment response relative to weight outcomes (% median BMI) and eating disorder cognitions (Eati..

View full abstract

Grants

Awarded by National Institute of Mental Health


Awarded by National Institutes of Health


Funding Acknowledgements

Dr. Gorrell is supported by the National Institute of Mental Health (K23MH126201). Funding support for the original studies was provided by National Institutes of Health grants R01-MH-070621 (Dr Lock) and by a grant from the Baker Foundation (Australia). The Murdoch Children's Research Institute is supported by the Victorian Government's Operational Infrastructure Support Program.