Journal article

A toolbox for generating scalable mitral valve morphometric models

Diana C de Oliveira, Daniel M Espino, Luca Deorsola, Jonathan P Mynard, Vijay Rajagopal, Keith Buchan, Dana Dawson, Duncan ET Shepherd

COMPUTERS IN BIOLOGY AND MEDICINE | PERGAMON-ELSEVIER SCIENCE LTD | Published : 2021

Abstract

The mitral valve is a complex anatomical structure, whose shape is key to several traits of its function and disease, being crucial for the success of surgical repair and implantation of medical devices. The aim of this study was to develop a parametric, scalable, and clinically useful model of the mitral valve, enabling the biomechanical evaluation of mitral repair techniques through finite element simulations. MATLAB was used to parameterize the valve: the annular boundary was sampled from a porcine mitral valve mesh model and landmark points and relevant boundaries were selected for the parameterization of leaflets using polynomial fitting. Several geometric parameters describing the annu..

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