Journal article

Doppler Ultrasound of the Fetal Descending Aorta: An Objective Tool to Assess Placental Blood Flow Resistance in Pregnancies with Discordant Umbilical Arteries.

Lindsay S Cahill, Grace V Mercer, Dakshita Jagota, Anjana Ravi Chandran, Natasha Milligan, Shiri Shinar, Clare L Whitehead, Sebastian R Hobson, Lena Serghides, W Tony Parks, Christopher K Macgowan, John C Kingdom, John G Sled, Ahmet A Baschat

J Ultrasound Med | Published : 2021


OBJECTIVES: To determine the relationship between blood flow in the fetal descending aorta and discordant umbilical arteries (UAs). METHODS: Pulsed wave Doppler of both UAs and the descending aorta was performed at 4-weekly intervals between 14 and 40 weeks of gestation in 209 pregnant women. In datasets with discordant UAs, a linear mixed effects model was used to determine the categorical relationship between the UA pulsatility index (PI) (high, low and average) and the descending aorta PI. RESULTS: Of the 209 cases, 81 had a discordance of greater than 25% in UA PI during one of their visits. There were no differences in birth outcomes between the groups with concordant and discordant UA ..

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Awarded by NICHD NIH HHS

Awarded by Eunice Kennedy Shriver National Institute of Child Health and Human Development