Journal article

PECARN algorithms for minor head trauma: Risk stratification estimates from a prospective PREDICT cohort study

Silvia Bressan, Nitaa Eapen, Natalie Phillips, Yuri Gilhotra, Amit Kochar, Sarah Dalton, John A Cheek, Jeremy Furyk, Jocelyn Neutze, Amanda Williams, Stephen Hearps, Susan Donath, Ed Oakley, Sonia Singh, Stuart R Dalziel, Meredith L Borland, Franz E Babl



BACKGROUND: The Pediatric Emergency Care Applied Research Network (PECARN) head trauma clinical decision rules informed the development of algorithms that risk stratify the management of children based on their risk of clinically important traumatic brain injury (ciTBI). We aimed to determine the rate of ciTBI for each PECARN algorithm risk group in an external cohort of patients and that of ciTBI associated with different combinations of high- or intermediate-risk predictors. METHODS: This study was a secondary analysis of a large multicenter prospective data set, including patients with Glasgow Coma Scale scores of 14 or 15 conducted in Australia and New Zealand. We calculated ciTBI rates ..

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Awarded by National Health and Medical Research Council (Centre of Research Excellence for Paediatric Emergency Medicine), Canberra, Australia

Awarded by Emergency Medicine Foundation, Brisbane, Australia

Awarded by Perpetual Philanthropic Services, Australia

Awarded by Auckland Medical Research Foundation, Auckland, New Zealand

Awarded by Health Research Council of New Zealand

Funding Acknowledgements

This study was funded by grants from the National Health and Medical Research Council (project grant GNT1046727, Centre of Research Excellence for Paediatric Emergency Medicine GNT1771228), Canberra, Australia; the Murdoch Children's Research Institute, Melbourne, Australia; the Emergency Medicine Foundation (EMPJ-11162), Brisbane, Australia; Perpetual Philanthropic Services (2012/1140), Australia; Auckland Medical Research Foundation (No. 3112011) and the A+ Trust (Auckland District Health Board), Auckland, New Zealand; WA Health Targeted Research Funds 2013, Perth, Australia; the Townsville Hospital and Health Service Private Practice Research and Education Trust Fund, Townsville, Australia; and supported by the Victorian Government's Infrastructure Support Program, Melbourne, Australia. FEB's time was part funded by an NHMRC Practitioner Fellowship, Canberra, Australia and a Melbourne Campus Clinician Scientist fellowship, Melbourne, Australia. SRD's time was part funded by the Health Research Council of New Zealand (HRC13/556) and Cure Kids New Zealand.