Journal article
Development of brain white matter and math computation ability in children born very preterm and full-term
SE Collins, DK Thompson, CE Kelly, JYM Yang, L Pascoe, TE Inder, LW Doyle, JLY Cheong, AC Burnett, PJ Anderson
Developmental Cognitive Neuroscience | Published : 2021
Abstract
Children born very preterm (VPT; <32 weeks’ gestation) have alterations in brain white matter and poorer math ability than full-term (FT) peers. Diffusion-weighted magnetic resonance imaging studies suggest a link between white matter microstructure and math in VPT and FT children, although longitudinal studies using advanced modelling are lacking. In a prospective longitudinal cohort of VPT and FT children we used Fixel-Based Analysis to investigate associations between maturation of white matter fibre density (FD), fibre-bundle cross‐section (FC), and combined fibre density and cross‐section (FDC) and math computation ability at 7 (n = 136 VPT; n = 32 FT) and 13 (n = 130 VPT; n = 44 FT) ye..
View full abstractRelated Projects (1)
Grants
Awarded by Murdoch Children's Research Institute
Funding Acknowledgements
This research was supported by the Australian Government Research Training Program Scholarship (to SEC) , the Australian National Health Medical Research Council (NHMRC; Centre for Research Excellence 546519, 1060733 and 1153176; Project Grant 237117, 491209 and 1066555; Senior Research Fellowship 1081288 to PJA; Investigator Grant 1176077 to PJA; Career Development Fellowships 1085754 and 1160003 to DKT and 1141354 to JLYC, and; Early Career Fellowship 1012236 to DKT) , the Murdoch Children's Research Institute, the Royal Children's Hospital, the Royal Children's Hospital Foundation (RCH1000 to JYMY) , the Department of Paediatrics at the University of Melbourne, and the Victorian Government's Operational Infrastructure Support Program. The funding organizations/sponsors had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.