Voltage-sensitive sodium channel (Vssc) mutations associated with pyrethroid insecticide resistance in Aedes aegypti (L.) from two districts of Jeddah, Kingdom of Saudi Arabia: baseline information for a Wolbachia release program
Nancy M Endersby-Harshman, AboElgasim Ali, Basim Alhumrani, Mohammed Abdullah Alkuriji, Mohammed B Al-Fageeh, Abdulaziz Al-Malik, Mohammed S Alsuabeyl, Samia Elfekih, Ary A Hoffmann
PARASITES & VECTORS | BMC | Published : 2021
BACKGROUND: Dengue suppression often relies on control of the mosquito vector, Aedes aegypti, through applications of insecticides of which the pyrethroid group has played a dominant role. Insecticide resistance is prevalent in Ae. aegypti around the world, and the resulting reduction of insecticide efficacy is likely to exacerbate the impact of dengue. Dengue has been a public health problem in Saudi Arabia, particularly in Jeddah, since its discovery there in the 1990s, and insecticide use for vector control is widespread throughout the city. An alternative approach to insecticide use, based on blocking dengue transmission in mosquitoes by the endosymbiont Wolbachia, is being trialed in Je..View full abstract
Awarded by KACST-CSIRO co-investment collaborative research agreement
The study was funded under the KACST-CSIRO co-investment collaborative research agreement [ETSC&KACST-CSIRO-2018-12-30-21] on "Management strategies of vector-borne disease in Saudi Arabia: feasibility of the Wolbachia-based approach as an alternative to chemical pesticides."