Acute Stroke Imaging Research Roadmap IV: Imaging Selection and Outcomes in Acute Stroke Clinical Trials and Practice
Bruce C Campbell, Maarten G Lansberg, Joseph P Broderick, Colin P Derdeyn, Pooja Khatri, Amrou Sarraj, Jeffrey L Saver, Achala Vagal, Gregory W Albers
STROKE | LIPPINCOTT WILLIAMS & WILKINS | Published : 2021
BACKGROUND AND PURPOSE: The Stroke Treatment Academic Industry Roundtable (STAIR) sponsored an imaging session and workshop during the Stroke Treatment Academic Industry Roundtable XI via webinar on October 1 to 2, 2020, to develop consensus recommendations, particularly regarding optimal imaging at primary stroke centers. METHODS: This forum brought together stroke neurologists, neuroradiologists, neuroimaging research scientists, members of the National Institute of Neurological Disorders and Stroke, industry representatives, and members of the US Food and Drug Administration to discuss imaging priorities in the light of developments in reperfusion therapies, particularly in an extended ti..View full abstract
Awarded by National Institutes of Health
Dr Lansberg reports research support from the National Institutes of Health. Dr Broderick reports research support from the National Institutes of Health (U01NS086872), other from Genentech, other from Ono Pharmaceutical, and other from Basking Bioscience outside the submitted work. Dr Derdeyn reports grants from Siemens Healthineers, other from Penumbra, other from Silk Road, other from NoNo, and other from Euphrates Vascular outside the submitted work. Dr Khatri declares payments from the National Institutes of Health, Nervive, and Cerenovus as grants, Lumosa, Basking Biosciences, Diamedica as a consultant, and Bayer for her role as National Leader for a clinical trial. Dr Sarraj reports grants and personal fees from Stryker Neurovascular outside the submitted work. Dr Saver reports serving as an unpaid site investigator in multicenter trials sponsored by Covidien/Medtronic, Abbott, Stryker, and Neuravi/Cerenovus, for which the University of California received payments on the basis of clinical trial contracts for the number of subjects enrolled; reports receiving contracted hourly payments and travel reimbursement from Covidien, Medtronic/Abbott, Stryker, and Neuravi/Abbott, and stock options from Rapid Medical, for service on Trial Steering Committees, advising on rigorous trial design and conduct. The University of California has patent rights in retrieval devices for stroke. Dr Vagal reports research support from the National Institutes of Health (R01NS103824, RF1NS117643, R01NS100417, U01NS100699, U01NS110772) and research grant from Cerenovus to her department for her role as Director of Imaging Core Lab for clinical trial. Dr Albers reports research support from the National Institutes of Health (U01NS092076 and 1U10NS086487), equity interest in iSchemaView, and consulting fees from Genentech and iSchemaView. The other author reports no conflicts.