Journal article
Elevated HDL Levels Linked to Poorer Cognitive Ability in Females With Parkinson’s Disease
MC Bakeberg, AM Gorecki, JE Kenna, A Jefferson, M Byrnes, S Ghosh, MK Horne, S McGregor, R Stell, S Walters, FL Mastaglia, RS Anderton
Frontiers in Aging Neuroscience | FRONTIERS MEDIA SA | Published : 2021
Abstract
Introduction: Cholesterol levels have been associated with age-related cognitive decline, however, such an association has not been comprehensively explored in people with Parkinson’s disease (PD). To address this uncertainty, the current cross-sectional study examined the cholesterol profile and cognitive performance in a cohort of PD patients. Methods: Cognitive function was evaluated using two validated assessments (ACE-R and SCOPA-COG) in 182 people with PD from the Australian Parkinson’s Disease Registry. Total cholesterol (TC), high-density lipoprotein (HDL), low-density lipoprotein (LDL), and Triglyceride (TRG) levels were examined within this cohort. The influence of individual lipid..
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Funding Acknowledgements
This study was supported by the Perron Institute for Neurological and Translational Science and Federal Cooperative Research Centre for Mental Health (CRCMH). This research was carried out while MB, AG, and JK were in receipt of Australian Government Domestic Research Training Program Stipends at The University of Western Australia, and MB was in receipt of a Richard Walter Gibbon Medical Research Scholarship.