Journal article

The Therapeutic Potential of Wogonin Observed in Preclinical Studies

Javad Sharifi-Rad, Jesus Herrera-Bravo, Luis A Salazar, Shabnum Shaheen, Seyed Abdulmajid Ayatollahi, Farzad Kobarfard, Muhammad Imran, Ali Imran, Luisa Custodio, Maria Dolores Lopez, Mauricio Schoebitz, Miquel Martorell, Manoj Kumar, Hafiz Ansar Rasul Suleria, William C Cho

EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE | HINDAWI LTD | Published : 2021

Abstract

Wogonin is a flavonoid found in different plants such as roots of Scutellaria baicalensis Georgi distributed mainly in Asia and Europe. Dried root extracts of S. baicalensis with high content of wogonin, popularly known as "Huang-Qin" or Chinese or baical skullcap, have been used for long time in traditional Chinese medicine. Several health benefits are attributed to wogonin and derivatives showing anti-inflammatory, antiviral, anticancer, and antioxidant effects and more recently antineurodegenerative properties. Preclinical pharmacological activities of wogonin against diverse types of cancer such as breast, colorectal, and human gastric cancer will be presented in this review. In addition..

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University of Melbourne Researchers