Global patterns in genomic diversity underpinning the evolution of insecticide resistance in the aphid crop pest Myzus persicae.
Kumar Saurabh Singh, Erick MG Cordeiro, Bartlomiej J Troczka, Adam Pym, Joanna Mackisack, Thomas C Mathers, Ana Duarte, Fabrice Legeai, Stéphanie Robin, Pablo Bielza, Hannah J Burrack, Kamel Charaabi, Ian Denholm, Christian C Figueroa, Richard H Ffrench-Constant, Georg Jander, John T Margaritopoulos, Emanuele Mazzoni, Ralf Nauen, Claudio C Ramírez Show all
Commun Biol | Published : 2021
The aphid Myzus persicae is a destructive agricultural pest that displays an exceptional ability to develop resistance to both natural and synthetic insecticides. To investigate the evolution of resistance in this species we generated a chromosome-scale genome assembly and living panel of >110 fully sequenced globally sampled clonal lines. Our analyses reveal a remarkable diversity of resistance mutations segregating in global populations of M. persicae. We show that the emergence and spread of these mechanisms is influenced by host-plant associations, uncovering the widespread co-option of a host-plant adaptation that also offers resistance against synthetic insecticides. We identify both t..View full abstract
Awarded by Biotechnology and Biological Sciences Research Council