Journal article

Effects of immunosuppression on the efficacy of vaccination against Mycoplasma gallisepticum infection in chickens

Sathya N Kulappu Arachchige, Anna Kanci Condello, Ling Zhu, Pollob K Shil, Kelly A Tivendale, Gregory J Underwood, Amir H Noormohammadi, Glenn F Browning, Nadeeka K Wawegama

VETERINARY MICROBIOLOGY | ELSEVIER | Published : 2021

Abstract

Immunosuppression can increase the susceptibility of chickens to other disease-causing pathogens and interfere with the efficacy of vaccination against those pathogens. Chicken anaemia virus (CAV) and infectious bursal disease virus (IBDV) are common causes of immunosuppression in chickens. Immunosuppression was induced by experimental infection with either CAV or IBDV to assess the effect of immunosuppression on the efficacy of vaccination with Mycoplasma gallisepticum strain ts-304 against infection with virulent M. gallisepticum, a common bacterial pathogen of chickens worldwide. Birds were experimentally infected with either CAV or IBDV at 1 week of age, before vaccination and challenge ..

View full abstract