The role of Kingella kingae in pre-school aged children with bone and joint infections

Laudi Olijve; Lahiru Amarasena; Emma Best; Christopher Blyth; Mirjam van den Boom; Asha Bowen; Penelope A Bryant; Jim Buttery; Hazel C Dobinson; Joshua Davis; Joshua Francis; Heidi Goldsmith; Elle Griffiths; Te-Yu Hung; Julie Huynh; Alison Kesson; Andrea Meehan; Brendan McMullan; Clare Nourse; Pamela Palasanthiran; Rushi Penumarthy; Katie Pilkington; Janine Searle; Anya Stephenson; Rachel Webb; Jonathan Williman; Tony Walls

Journal article

The role of Kingella kingae in pre-school aged children with bone and joint infections

Laudi Olijve, Lahiru Amarasena, Emma Best, Christopher Blyth, Mirjam van den Boom, Asha Bowen, Penelope A Bryant, Jim Buttery, Hazel C Dobinson, Joshua Davis, Joshua Francis, Heidi Goldsmith, Elle Griffiths, Te-Yu Hung, Julie Huynh, Alison Kesson, Andrea Meehan, Brendan McMullan, Clare Nourse, Pamela Palasanthiran Show all

JOURNAL OF INFECTION | W B SAUNDERS CO LTD | Published : 2021

DOI: 10.1016/j.jinf.2021.06.028

Abstract

OBJECTIVES: The Pre-school Osteoarticular Infection (POI) study aimed to describe the burden of disease, epidemiology, microbiology and treatment of acute osteoarticular infections (OAI) and the role of Kingella kingae in these infections. METHODS: Information about children 3-60 months of age who were hospitalized with an OAI to 11 different hospitals across Australia and New Zealand between January 2012 and December 2016 was collected retrospectively. RESULTS: A total of 907 cases (73%) were included. Blood cultures grew a likely pathogen in only 18% (140/781). The peak age of presentation was 12 to 24 months (466/907, 51%) and Kingella kingae was the most frequently detected microorganism..

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University of Melbourne Researchers

Jim Buttery Author Paediatrics Royal Children's Hospital

Grants

Awarded by National Health and Medical Research Council

Awarded by Australia's National Health and Medical Research Council

Funding Acknowledgements

AB receives Investigator Award funding from the National Health and Medical Research Council (1175509). CCB receives Investigator Award funding from the National Health and Medical Research Council (1173163). PAB is in receipt of a Murdoch Children's Research Institute Clinician Scientist Fellowship, and a National Health and Medical Research Council Investigator Grant. JSD receives salary funding from Australia's National Health and Medical Research Council (Fellowship number 1160331). BM is funded by a PhD scholarship from the University of Melbourne. JRF Receives funding from Department of Foreign Affairs and Trade, IndoPacific centre for Health Security and UK Aid Fleming Fund.