315 ASSOCIATION OF LOW DIASTOLIC BLOOD PRESSURE WITH INCREASED AMINO-TERMINAL-PRO-B-TYPE NATRIURETIC PEPTIDE LEVELS EXPLAINED BY COMORBIDITIES THAT INCREASE HEART FAILURE RISK

Abstract

Objective: To examine, in a cohort of adults at increased cardiovascular risk, the relationship between systolic (SBP), diastolic (DBP) and pulse (PP) pressures and amino-terminal-pro-B-type natriuretic peptide (NT-proBNP) levels. Design, setting and participants: A cross-sectional study of 3994 adults enrolled in the SCReening Evaluation of the Evolution of New Heart Failure (SCREEN-HF) study. Inclusion criteria were age ≥60 years with one or more of self-reported ischaemic or other heart disease, atrial fibrillation, cerebrovascular disease, renal impairment, or treatment for hypertension or diabetes for ≥2 years. Exclusion criteria were known heart failure or cardiac abnormality on echoca..