Young people's experiences of a CDH1 pathogenic variant: Decision-making about gastric cancer risk management
Cass Hoskins, Erin Tutty, Rebecca Purvis, Mary Shanahan, Alex Boussioutas, Laura Forrest
JOURNAL OF GENETIC COUNSELING | WILEY | Published : 2021
The most effective option for gastric cancer risk management in individuals with a CDH1 germline pathogenic or likely pathogenic variant (PV) in Australia is prophylactic total gastrectomy (PTG). There is, however, increasing confidence in endoscopic surveillance as a risk management strategy thus affording individuals with a CDH1 PV with challenging decisions regarding their gastric cancer risk management. For young people, this decision-making comes at a complex development stage of emerging and young adulthood. This study aims to explore the factors that influence young people's decision-making about their gastric cancer risk management due to a CDH1 PV. Potential participants were identi..View full abstract
This work was funded by a grant from the Peter MacCallum Foundation to C.H., and the authors gratefully acknowledge this support. The authors would also like to acknowledge and thank the young people who generously gave their time to participate in this study.