Journal article

Young people's experiences of a CDH1 pathogenic variant: Decision-making about gastric cancer risk management

Cass Hoskins, Erin Tutty, Rebecca Purvis, Mary Shanahan, Alex Boussioutas, Laura Forrest

JOURNAL OF GENETIC COUNSELING | WILEY | Published : 2021

Abstract

The most effective option for gastric cancer risk management in individuals with a CDH1 germline pathogenic or likely pathogenic variant (PV) in Australia is prophylactic total gastrectomy (PTG). There is, however, increasing confidence in endoscopic surveillance as a risk management strategy thus affording individuals with a CDH1 PV with challenging decisions regarding their gastric cancer risk management. For young people, this decision-making comes at a complex development stage of emerging and young adulthood. This study aims to explore the factors that influence young people's decision-making about their gastric cancer risk management due to a CDH1 PV. Potential participants were identi..

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