Functional and patient-reported changes in swallowing and voice after combined chemotherapy and radiotherapy for limited-stage small-cell lung cancer
Jacqui Frowen, Karla Gough, Rhys Hughes, Allison Drosdowsky, Mary Duffy, Nicole Kiss, Jo Phipps-Nelson, Shankar Siva, Benjamin Solomon, David Ball
JOURNAL OF MEDICAL IMAGING AND RADIATION ONCOLOGY | WILEY | Published : 2021
INTRODUCTION: The purpose of this study was to describe the nature and impact of dysphagia and dysphonia in patients with limited-stage small-cell lung cancer (SCLC) before and after chemoradiation. METHODS: A prospective cohort study was conducted on patients receiving chemoradiotherapy for limited-stage SCLC. Patients received either 40, 45 or 50 Gy, commencing the second cycle of chemotherapy. Outcomes included: videofluoroscopy (VFSS) to investigate aspiration, swallowing function and oesophageal motility; oral intake limitations; patient-reported dysphagia; and patient-reported dysphonia. Data were collected before treatment and one, three and six months post-treatment. RESULTS: Twelve ..View full abstract
This work was supported by the Victorian Cancer Agency (VCA) through which the first author was a recipient of an Early Career Seed Grant.