Journal article

Systems-Level Change to Alleviate Barriers to Cancer Clinical Trial Access for Adolescents and Young Adults in Australia

JA Ellis, VS Malalasekera, C Allan, PF Choong, JR Hansford, R Hehir, N Morello, S O'Callaghan, L Orme, N Phillipson, MA Rosenthal, S Sawyer, R Strong, L Super, A Watt, C Williams, A Woollett, A Robertson, J Lewin

Journal of Adolescent and Young Adult Oncology | MARY ANN LIEBERT, INC | Published : 2022

Abstract

Purpose: International data demonstrate association between clinical trial participation and reduced cancer mortality. Adolescents and young adults (AYA) have low clinical trial enrollment rates. We established a program to understand local barriers and develop targeted solutions that lead to greater AYA clinical trial participation. Methods: A steering committee (SC) with expertise in adult and pediatric oncology, research ethics, and consumer representation was formed. The SC mapped barriers related to AYA trial access and established working groups (WGs) around three themes. Results: The Regulatory Awareness WG identified a lack of understanding of processes that support protocol approval..

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