Journal article

Contemporary management of locoregionally advanced melanoma in Australia and New Zealand and the role of adjuvant systemic therapy

B Mark Smithers, Robyn PM Saw, David E Gyorki, Richard CW Martin, Victoria Atkinson, Andrew Haydon, Rachel Roberts-Thomson, John F Thompson



Australia and New Zealand have the highest incidence and mortality rates for melanoma in the world. Local surgery is still the standard treatment of primary cutaneous melanoma, and it is therefore important that surgeons understand the optimal care pathways for patients with melanoma. Accurate staging is critical to ensure a reliable assessment of prognosis and to guide treatment selection. Sentinel node biopsy (SNB) plays an important role in staging and the provision of reliable prognostic estimates for patients with cutaneous melanoma. Patients with stage III melanoma have a substantial risk of disease recurrence following surgery, leading to poor long-term outcomes. Systemic immunotherap..

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Funding Acknowledgements

The authors thank Theresa Wade of WriteSource Medical Pty Ltd., Sydney, Australia, for providing medical writing support by developing the first draft of the manuscript based on input from coauthors during an initial teleconference, with subsequent finalisation of the manuscript after all authors had had the opportunity to comment and edit subsequent versions. The medical writing support was funded by Novartis, Sydney, Australia in accordance with Good Publication Practice (GPP3) guidelines.