Journal article

Comparing the Prognostic Impact of Age and Baseline National Institutes of Health Stroke Scale in Acute Stroke due to Large Vessel Occlusion

Johanna Maria Ospel, Scott Brown, Manon Kappelhof, Wim van Zwam, Tudor Jovin, Daniel Roy, Bruce C Campbell, Peter Mitchell, Yvo Roos, Francis Guillemin, Brian Buck, Keith Muir, Serge Bracard, Phil White, Richard du Mesnil de Rochemont, Mayank Goyal



Background and Purpose: Little is known about the combined effect of age and National Institutes of Health Stroke Scale (NIHSS) in endovascular treatment (EVT) for acute ischemic stroke due to large vessel occlusion, and it is not clear how the effects of baseline age and NIHSS on outcome compare to each other. The previously described Stroke Prognostication Using Age and NIHSS (SPAN) index adds up NIHSS and age to a 1:1 combined prognostic index. We added a weighting factor to the NIHSS/age SPAN index to compare the relative prognostic impact of NIHSS and age and assessed EVT effect based on weighted age and NIHSS. Methods: We performed adjusted logistic regression with good outcome (90-day..

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